at is the difference between freehand and fireworks
The difference is, is that Freehand is for graphic design for designers who need very high dpi images and the file size is not a problem because its for print or t-shirts or a book or something (anything)
Fireworks on the other hand (pun -haha) is for web design. It only allows you to have 72 dpi. It also includes a lot of features which enhance sites.