I am a bit in the Twilight Zone currently of what to focus on.

1. HTML5 Javascript
That seems to be an area everybody is jumping on. I see that at least one should know some basics. However, because of Javascript, which is not a real programming language I have my doubts the hype will continue forever. I also hear that actually many people who are serious programmers don't think much of that. Your opinion?

2. Flash, Flash builder
That is what I know and I think sticking to AIR applications is not time lost. I am developing scientific applications with that, since I am Biologist. Does AIR have a future?
Is worthwhile to get into Flash for mobile or will that sooner or later disappear?

3. 3D
However, I missed all the 3D development (Molehill, away3D etc). Is that worthwhile getting into at this stage?
I have Swift 3D and know to some extent how to use it. Is that something, which still has a future and is worthwhile following up?

Thanks for any advice. I know there are some threads on that but there is just small bits of information.