OM2,

Why not just build your PC and Mac (if you need a cross-platform CD) in flash? You can just create an autorun.inf file to handle the self-launching (assuming the user has autorun enabled) on the PC side. I believe OSX signaled the end of autorunning on the Mac side.

I've never had a flash published exe not run on any Windows OS...

Flex is just for building Mobile or Web delivered applications.

Hope that helps!