I would create a function to Disable all buttons then call that function from your clicked function.

function disableButtons():void{
aa1.removeEventListener(MouseEvent.CLICK, ona1Click);
bb1.removeEventListener(MouseEvent.CLICK, onb1Click);
cc1.removeEventListener(MouseEvent.CLICK, onc1Click);
//or as steven FN said, you can use the .mouseEnabled method
}

funtion onb1Click(e:MouseEvent):void{
//all of your other code
disableButtons();
}