How to disable a button/action after a single click?

[fx.barrett]

yourMovieClip.addEventListener(MouseEvent.MOUSE_UP, mouseUpHandler);

function mouseUpHandler(event:MouseEvent):void 
{
   gotoAndPlay(2);
   event.target.removeEventListener(MouseEvent.MOUSE_UP, mouseUpHandler);
} 

Use target instead of currentTraget, it should work.