Since you said spoilers... here's my rant.

Wolverine did not willingly go into the Weapon X program and get adamantium injected into him willingly. Stryker was a reverend that had ties to the Weapon X program, not a general. Wade, aka Deadpool had cancer and was indeed Weapon XI, but he did not have two swords, nor laser eyes nor did he never talk - he's the "Merc with a Mouth" for goodness sake. That was NOT Emma Frost... she's a psychic. Agent Zero was not Asian, he was German. And they totally screwed up the origin of Wolverine something fierce.

Was Patrick Stewart CGI? It looked like it.

Sabretooth... they changed dudes twice? The original one was better imho than this one.

There are others... many other nitpicks and issues with the movie. But the story alone is a problem. WTF.